Combined forced oscillation and forced expiration measurements in mice for the assessment of airway hyperresponsiveness
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چکیده
منابع مشابه
Combined forced oscillation and forced expiration measurements in mice for the assessment of airway hyperresponsiveness
BACKGROUND Pulmonary function has been reported in mice using negative pressure-driven forced expiratory manoeuvres (NPFE) and the forced oscillation technique (FOT). However, both techniques have always been studied using separate cohorts of animals or systems. The objective of this study was to obtain NPFE and FOT measurements at baseline and following bronchoconstriction from a single cohort...
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BACKGROUND The contribution of the pulmonary tissues to the mechanical behaviour of the respiratory system is well recognised. This study was undertaken to detect airway and lung tissue responses to inhaled methacholine (Mch) using the low frequency forced oscillation technique (LFOT). METHODS The respiratory system impedance (Zrs, 0.5-20 Hz) was determined in 17 asymptomatic infants. A model...
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The measurement of forced expiratory volume in one second (FEV1) is often used to assess the effect of bronchial provocations, and deep inspiration is required beforehand. This may briefly alter the bronchial tone in a variable way in some subjects. The forced oscillation technique (FOT) is a test used to characterize the mechanical impedance of the respiratory system, and prior deep inspiratio...
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A non-invasive index of airway distensibility is required to track airway remodeling over time. The forced oscillation technique (FOT) provides such an index by measuring the change in respiratory system conductance at 5 Hz over the corresponding change in lung volume (ΔGrs5/ΔVL). To become useful clinically, this method has to be reproducible and easy to perform. The series of breathing maneuv...
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ژورنال
عنوان ژورنال: Respiratory Research
سال: 2010
ISSN: 1465-993X
DOI: 10.1186/1465-9921-11-82